Once a cleanroom is built, the hvac system is operating and all equipment is installed, a meticulous initial clean is required prior to validation and use. This may require a facility shut down clean.
THIS IMPORTANT EVENT IS PERFORMED RAPIDLY, UNDER CLOSE CONTROL AND WITHIN THE CGMPS
PHASE ONE: Pre-shutdown activities (planning and scheduling)
PHASE TWO: Declassification and handover
PHASE THREE: Day-to-day management and handover
PHASE FOUR: Reclassification and handover
PHASE FIVE: Post-shutdown activities and completion of the shutdown report