Ionized Hydrogen Peroxide (iHP™)
Superior Life Sciences Disinfection & Decontamination
Maintaining an environment that is comfortable and free of contagions is essential to produce the most accurate research findings for our world in the life sciences realm, especially for those scientists working in biosafety laboratories who routinely handle the most lethal microorganisms known to science. Utilizing a decontaminant that is effective against pathogens and won’t harm sensitive laboratory equipment is essential to maintaining a productive work environment for these environments.
SteraMist, powered by Binary Ionization Technology (BIT), offers your life sciences facility superior material compatibility and boasts significant efficacy compared to other decontamination options, capable of eliminating all contamination challenges within critical environments faster than any competitors on the market and without the production of byproducts.
iHP™ Technology Explained
Step 1
7.8% Hydrogen Peroxide Bit™ Solution converts to iHP™ after passing through a cold plasma arc.
Step 2
iHP™ is carried thought the mist, moving like a gas throughout the treated area.
Step 3
iHP™ damages pathogenic organisms through oxidation of proteins, carbohydrates and lipids.
Step 4
iHP™ cellular disruption and/or dysfunctions occur and allows for disinfection and decontamination in the targeted area.
A. Electrodes
B. Nozzle
C. Atmospheric Cold Plasma Arc
D. ionized Hydrogen Peroxide (iHP™)
The atmospheric cold plasma arc converts the H2O2 molecules into iHP™. As one of the most powerful oxidizing agents in nature, the iHP™ kills the pathogens achieving high efficacy and leaves behind only oxygen and humidity in treated spaces.
iHP™ Technology Efficacy
Independent testing had proven six-log (99.9999%) efficacy against the gold standard for sterilization, Geobacillus stearothermophilus and Bacillus atrophaeus – a notoriously difficult to kill spore.
With this development, further EPA testing had placed it on the following Lists:
LIST G: Norovirus
LIST H: MRSA
LIST K: C. difficile spores
LIST L: Ebola
LIST M: H1N1
LIST N: Emerging Pathogens, Including SARS-CoV-2 Coronavirus
iHP™ Features Efficacy Against:
- Pseudomonas
- H1N1 (Influenza A Virus)
- Salmonella
- C. diff (Clostridium difficile) Spores
- Geobacillus Stearothermophilus Spores
- Staphylococcus
- Norovirus
- Mold & Mildew
- MRSA
- Adenovirus
iHP™ Technology History
Ionized Hydrogen Peroxide (iHP™) was developed as a direct response to weaponized anthrax attacks As an invention funded by a grant provided by the U.S. Defense Advanced Research Projects Agency (DARPA).
The Defense Advanced Research Projects Agency (DARPA) is a research and development agency of the United States Department of Defense responsible for the development of emerging technologies for use by the US military.
Complete Room Fogging Decontamination System
lonized Hydrogen Peroxide can achieve 6-log organism reduction on:
Bactericide
Virucide
- Application time: taking only 5 seconds per square foot to apply.
- Contact time to disinfect: 7-minute.
- Does not damage equipment so rooms do not need to be emptied. Even highly technical equipment can be left out.
- Does not leave any toxic residue. There is no need to wipe or rinse surfaces. Can reach the entire room, leaving no surface untreated by human error and is even effective on hard-to-clean surfaces.
- Easy to integrate with cleaning procedures.
- Is validated to comply with Good Manufacturing Practice (GMP) standards.
SteraMist™ is designed to provide confidence that facilities have been efficiently and effectively decontaminated with a Six-Log reduction.
With the advanced technology and reliance on the power of the hydroxyl radical and not the high percentage of hydrogen peroxide, SteraMist™ returns a facility back to operations faster than any other competing technology, with no corrosive impact on sensitive and expensive equipment.
Complete disinfection/decontamination solutions for airborne and surface contamination in all environments, including those that follow cGMP and cGLP specifications.
SteraMist™ provides dedicated bio-decontamination solutions with a focus on use sites in Pharmaceutical, Biotechnology, Hospital, Pharmacy, Laboratory and Bio-safety industries.
To meet specific customer and regulatory requirements, SteraMist™ is able to offer a range of disinfection/decontamination solutions suitable for regulatory controlled aseptic processing facilities from BSL-3 and BSL-4 laboratories through to large research establishments.
SteraMist™ is a decontamination system created by TOMI Environmental Solutions, Inc.
SteraMist™ disinfection and decontamination is an EPA-registered solution and equipment combination fogger featuring a 7.8% hydrogen peroxide sole active ingredient.
SteraMist™ brings you unparalleled material compatibility with a wide variety of use sites.
The use of ionized Hydrogen Peroxide (iHP) technology creates natural, powerful particles that spread throughout large and small areas, reaching the toughest spots and goes far beyond manual cleaning and other disinfection methods.
SteraMist™ Custom Build-In
For a facility with unique requirements, SteraMist BIT may be permanently incorporated to any volume of space to achieve area decontamination. Fully automated with downloadable data. Product performance supported by GLP efficacy data.
Integrated Custom Decontamination Includes:
- Pass-Through Chamber
- Clean Rooms (including core areas)
- Fixed Room/Cabinet Systems
- Isolators
- Biosafety Cabinets (BSCs)
- Glove Boxes
- RABS Lines
- Tissue Banks
- Pharmaceutical Mnfg Production Lines
- Complete Sterile Mnfg Environments
iHP Competitive Advantage Analysis
VHP vs iHP
STERAMIST® iHP™ | vs | CHLORINE DIOXIDE |
|---|---|---|
| APPLICATION | ||
| ionized Hydrogen Peroxide (iHP™) can be applied to every surface, including sensitive electronics. | May cause progressive damage to room surfaces and equipment not protected from fumigation. | |
| UV INTERACTION | ||
| SteraMist® iHP™ is unaffected by the presence of UV lights. | Requires shutoff of lights, as chlorine dioxide breaks down in the presence of UV rays. | |
| OPERATION | ||
| Does not require room preconditioning, and point-and-spray application requires no rinsing or wiping. | Five Stage Operation: Preconditioning, Conditioning, Charging, Controlled Air, and Aeration. | |
| ODOR | ||
| SteraMist® iHP™ leaves no odor. | Smell of chlorine remains after treatment. | |
| STARTUP & PLACEMENT | ||
| SteraMist® automation allows for remote start, and the unit can remain in the area being treated. | Units should not be exposed to fumigant yet must remain in treated area to avoid inadvertent vent leaks. | |
MINNCARE vs iHP
iHP™ | vs | CANTEL MINNCARE |
|---|---|---|
| COMPOSITION | ||
| ionized Hydrogen Peroxide (iHP™) technology converts a 7.8% hydrogen peroxide solution into hydroxyl radicals. | Comprised of peracetic acid and hydrogen peroxide. | |
| PARTICLE SIZE | ||
| Features particle sizes as low as 0.04 microns to help get into spaces where most traditional cleaners can’t reach. | Filtered particle size of 0.2 microns. | |
| APPLICATION | ||
| Point-and-spray and full room system with no wiping or rinsing required, and leaves no residue. | Fogging system. | |
| ODOR | ||
| Fragrance-free. | Vinegar odor left behind after application | |
| CORROSION | ||
| SteraMist is non-corrosive. | Peracetic acid is known to be corrosive. | |
CHLORINE DIOXIDE vs iHP
| Organism | Classification | Log Reduction | Lab |
|---|---|---|---|
| Bacillus atrophaeus * | Bacterial Spore | >8.3 | 1 |
| Geobacillus stearothermophilus | Bacterial Spore | >6.3 | 3/6 |
| Bacillus subtilis | Bacterial Spore | >6.0 | 1 |
| Clostridium difficile spores *** | Bacterial Spore | >6.0 | 3/6 |
| Escherichia coli | Gram Negative | >7.4 | 2 |
| Pseudomonas aeruginosa *** | Gram Negative | >6.0 | 5/6 |
| Serratia marcescens | Gram Negative | >6.0 | 3 |
| Salmonella enterica *** | Gram Negative | >5.5 | 7 |
| Staphylococcus aureus *** | Gram Positive | >7.4 | 2/6 |
| Methicillin-resistant Staphylococcus aureus (MRSA) *** | Gram Positive | >5.9 | 6 |
| Bacillus atrophaeus vegetative cells | Gram Positive | >9.0 | 1 |
| Asperigillus Niger | Mold | >8.0 | 4 |
| Aspergillus species | Mold | >7.0 | 2 |
| Cladosporium species | Mold | >7.0 | 2 |
| Pencillium species | Mold | >7.0 | 2 |
| Stachybotrys chartarum | Mold | >7.0 | 4 |
| Trichophyton mentagrophytes | Mold | >6.0 | 4 |
| Human rhinovirus 16 ** | Virus | >6.8 | 3 |
| Influenza A (H1N1) *** | Virus | >10 | 6 |
| Norovirus *** | Virus | >6.4 | 7 |
| Adenovirus | Virus | >5.8 | 7 |
CLOROX TOTAL 360 vs iHP
STERAMIST® iHP™ | vs | CANTEL MINNCARE |
|---|---|---|
| COMPOSITION | ||
| ionized Hydrogen Peroxide (iHP™) technology converts a 7.8% hydrogen peroxide solution into hydroxyl radicals. | Comprised of peracetic acid and hydrogen peroxide. | |
| PARTICLE SIZE | ||
| Features particle sizes as low as 0.04 microns to help get into spaces where most traditional cleaners can’t reach. | Filtered particle size of 0.2 microns. | |
| APPLICATION | ||
| Point-and-spray and full room system with no wiping or rinsing required, and leaves no residue. | Fogging system. | |
| ODOR | ||
| Fragrance-free. | Vinegar odor left behind after application | |
| CORROSION | ||
| SteraMist is non-corrosive. | Peracetic acid is known to be corrosive. | |
iHP Efficacy on Biological Organisms
Efficacy Against 42 Molds and Fungi
Utilizing proven iHP™ technology, we are able to provide a 106 reduction of viruses, spores, and fungi.
The results are summarized in the following table. In the following table spore loads for the referenced fungi were reduced from 107 spores/ cm2 to undetectable levels in 15 seconds.
| Organism | Classification | Log Reduction | Lab |
|---|---|---|---|
| Bacillus atrophaeus * | Bacterial Spore | >8.3 | 1 |
| Geobacillus stearothermophilus | Bacterial Spore | >6.3 | 3/6 |
| Bacillus subtilis | Bacterial Spore | >6.0 | 1 |
| Clostridium difficile spores *** | Bacterial Spore | >6.0 | 3/6 |
| Escherichia coli | Gram Negative | >7.4 | 2 |
| Pseudomonas aeruginosa *** | Gram Negative | >6.0 | 5/6 |
| Serratia marcescens | Gram Negative | >6.0 | 3 |
| Salmonella enterica *** | Gram Negative | >5.5 | 7 |
| Staphylococcus aureus *** | Gram Positive | >7.4 | 2/6 |
| Methicillin-resistant Staphylococcus aureus (MRSA) *** | Gram Positive | >5.9 | 6 |
| Bacillus atrophaeus vegetative cells | Gram Positive | >9.0 | 1 |
| Asperigillus Niger | Mold | >8.0 | 4 |
| Aspergillus species | Mold | >7.0 | 2 |
| Cladosporium species | Mold | >7.0 | 2 |
| Pencillium species | Mold | >7.0 | 2 |
| Stachybotrys chartarum | Mold | >7.0 | 4 |
| Trichophyton mentagrophytes | Mold | >6.0 | 4 |
| Human rhinovirus 16 ** | Virus | >6.8 | 3 |
| Influenza A (H1N1) *** | Virus | >10 | 6 |
| Norovirus *** | Virus | >6.4 | 7 |
| Adenovirus | Virus | >5.8 | 7 |
Efficacy Against Microbial Pathogens
Utilizing proven iHP™ technology, we are able to provide a 106 reduction of viruses, spores, and fungi.
| Aspergillus expansum | Geotrichum candidum | Penicillium roquefortii |
|---|---|---|
| Aspergillus parasiticus | Memnoniella echinata | Penicillium verrucosum |
| Aspergillus restrictus | Mucor racemosus | Penicillium brevicompactum |
| Aspergillus sydowii | Mycothecium verrucaria | Rhizopus stolonifer |
| Aspergillus tamarii | Paecilomyces lilacinus | Scopulariopsis asperula |
| Aspergillus terrusi | Paecilomyces varioti | Scopulariopsis brevicaulis |
| Aspergillus ustus | Penicillium atramentosu | Scopulariopsis brumptii |
| Aspergillus versicolor | Penicillium cluysogenum | Scopulariopsis chartarum |
| Aspergillus wentii | Penicillium citrinum | Stachybotrys chartarum |
| Cladosporium cladoporiodes Type 1 | Penicillium corylophilum | Trichoderma hamatum |
| Cladosporium cladosporiodes | Penicillium crustosum | Trichoderma harzianum |
| Cladosporium herbarum | Penicillium glandicola T | Trichoderma longibranchiatum |
| Cladosporium sphaerospermen | Penicillium griseofulvum | Ulocladium chartarum |
| Eurotium arnstelodami | Penicillium olsonii | Wallemia sebi |
Notes
* Bacillus astrophaues is a surrogate for Bacillus anthracic (Anthrax)
** Human Influenza virus (Flu) surrogate
*** EPA Registered
Testing Labs
1. University of South Florida Center for Biological Defense
2. Microbial Insights
3. L-3 Communications
4. Microbiotest
5. Beckman Coulter
6. Accuratus Labs (formerly ATS) EPA Testing Lab
7. Microchem
