Blog Posts

Cleanroom Blog and Recent News

Risk Management

Risk Management

Risk management is a vital component of good manufacturing practice (GMP) compliance in the pharmaceutical industry. GMP regulations require pharmaceutical companies to implement a risk-based approach to the identification, evaluation, and control of risks associated with the manufacture of their pr...

Tue Jun 06 2023

Quality Control

Quality Control

Quality control is an essential aspect of good manufacturing practice (GMP) compliance. GMP compliance is crucial for ensuring that pharmaceutical products are safe, effective, and of high quality. The primary goal of quality control is to ensure that pharmaceutical products meet the specified quali...

Thu Jun 01 2023

Sterilization Methods

Sterilization Methods

Sterilization of medical devices is a critical aspect of ensuring the safety and efficacy of medical procedures. A wide range of medical devices are used in healthcare, including surgical instruments, implants, catheters, and many others. These devices need to be free from any microorganisms that ma...

Mon May 29 2023

The Role of HEPA Filters in Cleanrooms

The Role of HEPA Filters in Cleanrooms

HEPA (High-Efficiency Particulate Air) filters are an essential component of cleanroom design. HEPA filters are designed to remove particles as small as 0.3 microns with an efficiency of 99.97%. HEPA filters are critical for maintaining the required level of cleanliness in cleanrooms. Here are some ...

Wed May 24 2023

HVAC Systems in Cleanrooms: Design and Performance Requirements

HVAC Systems in Cleanrooms: Design and Performance Requirements

HVAC (heating, ventilation, and air conditioning) systems are critical components of cleanroom design. HVAC systems in cleanrooms must maintain the required level of cleanliness, temperature, humidity, and air pressure to ensure a sterile and contaminant-free environment. HVAC system design and perf...

Fri May 19 2023

Cleanroom Design: Requirements and Best Practices

Cleanroom Design: Requirements and Best Practices

Cleanroom design is a critical component of maintaining a sterile and contaminant-free environment. The design of a cleanroom is essential to ensure that the required level of cleanliness is achieved and maintained. Cleanroom design requirements and best practices vary depending on the industry and ...

Tue May 16 2023

Types of Cleanrooms: Classification and Applications

Types of Cleanrooms: Classification and Applications

Cleanrooms are highly controlled environments used in various industries such as pharmaceuticals, biotechnology, microelectronics, and healthcare to maintain a sterile and contaminant-free environment. Cleanrooms are classified based on the level of cleanliness required for specific applications. Th...

Thu May 11 2023

Maintaining a Cleanroom Environment: Best Practices for Contamination Control

Maintaining a Cleanroom Environment: Best Practices for Contamination Control

Cleanroom environments are essential for various industries such as pharmaceuticals, biotechnology, microelectronics, and healthcare to ensure product quality and safety. Contamination in a cleanroom can have severe consequences, including product recalls, equipment damage, and even life-threatening...

Mon May 08 2023

Contamination Control in Cleanrooms: Key Elements

Contamination Control in Cleanrooms: Key Elements

Cleanrooms are specialized environments that are designed to maintain low levels of particulate and microbial contamination. These environments are critical in many industries, including pharmaceuticals, biotechnology, and electronics manufacturing. Contamination control is essential to ensure produ...

Wed May 03 2023

Vibraclean - Your Partner for Controlled Environments

Vibraclean - Your Partner for Controlled Environments

Vibraclean: Your Trusted Partner for Cleanroom Maintenance and GMP Consulting When it comes to maintaining the sterility of cleanrooms and critical environments, there's no room for error. That's where Vibraclean comes in. Founded in 1988, Vibraclean is a leading GMP consulting group and service pr...

Tue May 02 2023

Sterility Testing

Sterility Testing

Sterility testing is a critical component of pharmaceutical manufacturing. It is a process used to ensure that pharmaceutical products are free from any viable microorganisms, such as bacteria, fungi, and viruses, that may cause infection or harm to patients. The failure to perform proper sterility ...

Fri Apr 28 2023

Environmental Monitoring for Cleanrooms: Strategies for Effective Control

Environmental Monitoring for Cleanrooms: Strategies for Effective Control

Cleanrooms are critical environments for many industries, including pharmaceuticals, biotech, and electronics manufacturing. These environments require stringent control of particulate and microbial contamination to ensure product quality, safety, and efficacy. One essential aspect of maintaining th...

Tue Apr 25 2023

Why Contamination Control is Important

Why Contamination Control is Important

Contamination control is a critical aspect of cleanroom operations in GMP facilities. A cleanroom environment must be maintained at a level that is free of contaminants, which could compromise the integrity of the products being manufactured. Best practices for contamination control in cleanrooms a...

Thu Apr 20 2023

Types of Cleanroom and GMP Contamination

Types of Cleanroom and GMP Contamination

Cleanrooms and GMP facilities are designed to manufacture products that require a controlled environment, free from contaminants that can compromise product quality and safety. The products manufactured in these facilities are typically pharmaceuticals, biologics, medical devices, and other high-val...

Mon Apr 17 2023

Key Principles of Contamination Control

Key Principles of Contamination Control

Contamination control is a critical aspect of cleanroom operations in the pharmaceutical, biotechnology, and medical device industries. Cleanrooms and GMP facilities are designed to control and minimize the introduction, generation, and spread of contaminants that can compromise the integrity of the...

Wed Apr 12 2023

Clean Room Services, Decontamination and Biological Indicators (BIs)

Clean Room Services, Decontamination and Biological Indicators (BIs)

What is a BI? Vibraclean has over 30 years experience in decontamination services and GMP services in canada, cleaning rooms and biological sterilization is our expertise! A biological indicator is broadly defined as a characterized preparation of a specific microorganism that provides a defined and...

Thu Dec 08 2022

How to use and validate iHP Cycles

How to use and validate iHP Cycles

Ionized Hydrogen Peroxide (iHP) iHP is hydrogen peroxide which is split into reactive oxygen species (ROS) by Binary Ionization Technology (BIT) that increases the efficacy and effectiveness of its use as a disinfectant. iHP is also classified as a sterilant, meaning that it can achieve sterilizatio...

Thu Dec 08 2022

Manual Sporicide vs. iHP: A Comparison

Manual Sporicide vs. iHP: A Comparison

Vibraclean has 30 years working to eliminate and sterilize cleanroom facilities across Canada and the US. In this article we will explore the best approach and guidelines to dealing with biological sterilization of spores and bacteria offering the most effective and trustworthy decontamination and f...

Thu Dec 08 2022

Overview Hydrogen Peroxide Fogging

Overview Hydrogen Peroxide Fogging

Hydrogen Peroxide Fogging is a method of decontamination that releases aerosolized hydrogen peroxide into enclosed areas. Because of its ability to work on a molecular level, hydrogen peroxide fogging is a much more efficient and effective way of eliminating microbes than manual cleaning. Aerosolize...

Wed Dec 07 2022

Fogging with iHP, VHP or HPV

Fogging with iHP, VHP or HPV

It is important to identify the different hydrogen peroxide systems that are in use today, the different abbreviations associated with each and to highlight the differences between them. VHP refers to vaporised hydrogen peroxide and is a trademark of Steris who were one of the original pioneers in h...

Wed Dec 07 2022